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Ghana international Richard Kingson will continue in goal with Matt Gilks ruled out for up to two months with a broken kneecap. Youngster Mark Halstead has been recalled from a loan at Barrow as back-up.
Blackpool have no other new fitness concerns but are still missing long-term casualties Billy Clarke, Alex Baptiste and Louis Almond.
Blackpool manager Ian Holloway is looking forward to welcoming Mick McCarthy to Bloomfield Road tomorrow having cleared the air with his Wolves counterpart.
Holloway apologised to McCarthy over a misunderstanding which arose as the Tangerines boss tried to justify his controversial 10 changes at Aston Villa last week.
Holloway suggested McCarthy did not think he could win when he made wholesale changes for Wolves' visit to Manchester United last season.
Wolves were hit with a £25,000 suspended fine for fielding an understrength side in that match.
Blackpool could be subject to similar sanctions having been written to by the Premier League for an explanation for their team selection at Villa Park nine days ago.
Holloway intends to mount a robust defence of his actions - and has threatened to resign if fined - and is sorry for dragging McCarthy into the controversy.
Holloway claims he commented on the Wolves case without knowing the full facts when asked in his post-match press conference immediately after the game at Villa, which his side lost 3-2 to a late goal.
"He was unhappy with what I said - I have never been unhappy with Mick," said Holloway at another press conference.
"I didn't know what Mick said. One or two of you people [media] told me Mick said something and I responded to it.
"Mick did what he felt was right and I don't think she should have been fined.
"Mick is a great manager - if I even do half of what he has done I will be delighted. Mick and I haven't got a problem.
"But that story has gone, let's move on. I am just getting on with my team for Wolves - it's quite ironic that we play Wolves next."
Holloway respects the achievements of former Sunderland and Republic of Ireland boss McCarthy and feels Wolves' current lowly position in the Barclays Premier League is no reflection of their ability.
Wolves go into the game 19th in the table with just nine points from 13 games, six behind Blackpool.
Holloway is also surprised the Molineux side appear to have acquired a reputation for dirty play this season.
"Again that is an absolute load of poppycock," the Seasiders manager said. "They are a fantastically hard-working team.
"They play great football, they stayed up last year and they'll be desperate to stay up again this year.
"They had a great start last year and everyone was saying how great they were.
"Now all of a sudden a few borderline tackles have been highlighted and blown out of all proportion."
Wolves defender Christophe Berra is set to return.
The Scotland defender was forced to withdraw from last weekend's home defeat against Bolton shortly before kick-off with a sore knee.
Fellow centre-back Steven Mouyokolo has also been declared fit after suffering a knee injury in the early stages against the Trotters although he was able to complete the game.
Winger Matt Jarvis is expected to be fit despite missing part of training this week with a calf injury.
McCarthy admits Wolves are approaching the "defining period" of the season, saying: "We are getting good at taking positives out of defeats and I am sick of it. It is wearing a bit thin.
"We've played well enough in all the games recently.
"We always take the positives out of any game but it is time to get three points.
"In games when you are playing teams, like we've got in the next six or seven games, you've got to get points.
"It is it a defining period up to Christmas. With the position we are in now, we've got to get results and wins and we have to get them quickly.
"We can't wait any longer for them."
McCarthy insists he does not suffer sleepless nights through Wolves' current plight.
He also knows there is no magic formula for reviving their fortunes but believes Wolves are due a change of fortunes.
McCarthy said: "I sleep fine. I am preoccupied at times, more so when you are not winning, because when you are winning, you can have a happy, normal existence."
Holloway apologised to McCarthy over a misunderstanding which arose as the Tangerines boss tried to justify his controversial 10 changes at Aston Villa last week.
Holloway suggested McCarthy did not think he could win when he made wholesale changes for Wolves' visit to Manchester United last season.
Holloway claims he commented on the Wolves case without knowing the full facts when asked in his post-match press conference immediately after the game at Villa, which his side lost 3-2 to a late goal.
"He was unhappy with what I said - I have never been unhappy with Mick," said Holloway at another press conference. "I didn't know what Mick said. One or two of you people [media] told me Mick said something and I responded to it.
"Mick did what he felt was right and I don't think she should have been fined. Mick is a great manager - if I even do half of what he has done I will be delighted. Mick and I haven't got a problem."
Wolves winger Matt Jarvis hopes to play despite missing part of training this week with a calf injury.
Christophe Berra is set to return after missing the defeat at Bolton with a sore knee, while Steven Mouyokolo is also fit despite his own knee problem.
Blackpool
Doubtful: Adam (knee), Almond (shoulder/fitness), Keinan (unspecified)
Injured: Baptiste, Clarke, Gilks, Martin & Rachubka (all knee)
Wolves
Doubtful: Edwards (thigh), Jarvis (calf), Ward (leg)
Injured: Craddock (thigh), Guedioura (leg), Kightly (knee), Zubar (ankle)
MATCH PREVIEW
Strictly Come Dancing is in town this weekend, but at Bloomfield Road on Saturday Blackpool and Wolves fans will be hoping their sides have the x-factor.
In terms of our league position it's getting to that stage when you look at the gap already... I've said before we need to get three points from somewhere and the sooner the better
Wolves boss Mick McCarthy
The match pits the side with the worst home record in the Premier League against the team with the worst away form in a crunch encounter.
Ian Holloway's Blackpool have brought plenty of sparkle to the top flight this season, but have repeatedly allowed opposing teams to waltz through their defence and have the most porous backline in the division.
Wolves, meanwhile, have lost eight out of their last 10, including three on the trot, and are yet to win away this season. Like Blackpool, a series of impressive performances have too often failed to translate into points on the board, although Mick McCarthy is convinced it is a matter of time before his side find their rhythm.
MATCH FACTS
Head-to-head
• Blackpool haven't beaten Wolves in any competition since October 1968, a run of 14 meetings over 42 years.
• Wolves haven't lost a league game at Blackpool in nine visits, since a 7-2 defeat in January 1962 in the old Division One.
Have your say on this match
Blackpool
• There have been 45 goals scored in Blackpool's 13 Premier League matches this season - an average of 3.46 per match.
• The Seasiders have the worst defensive record in the top flight, conceding 26 goals.
• Blackpool have won only one of their five Premier League home matches.
Wolves
• Wolves have lost eight of their last 10 league matches. Their only victory in the last 12 was 2-1 at home to Manchester City on 30 October.
• They are the only team without a clean sheet in the Premier League. The last time they managed not to concede was a 0-0 draw at Fulham on 17 April.
• Wolves have only won four out of 44 Premier League away matches and it is nine on the road since they last tasted victory.
LEADING GOALSCORERS
Blackpool
Harewood: 4 goals (4 league); Adam: 4 goals (3 league)
Wolves
Fletcher: 4 goals (3 league); Ebanks-Blake: 3 goals (3 league); Milijas: 3 goals (1 league)
MATCH OFFICIALS
Referee: Mark Clattenburg
Assistant referees: Jake Collin & Andy Newbold
Fourth official: Graham Salisbury
LAST LEAGUE MATCH LINE-UPS
Blackpool (D0-0 v West Ham, a): Gilks (Kingson 46); Eardley, Cathcart, Evatt, Crainey, Adam, Vaughan, Grandin (Phillips 59), Taylor-Fletcher, Campbell (Harewood 67), Varney. Subs not used: Euell, Sylvestre, Edwards, Carney.
Wolves (L2-3 v Bolton, h): Hahnemann; Foley, Stearman, Mouyokolo, Elokobi, Hunt (Fletcher 66), Henry, Milijas, Jarvis, Doyle, Ebanks-Blake. Subs not used: Hennessey, Van Damme, Ward, D Jones, Bent, Mancienne.
Source: BBC Sport